Rabbit Vaccines

Overview

• Rabbits need to be regularly vaccinated to protect them against three potentially deadly diseases:
  • Myxomatosis
  • Rabbit Viral Haemorrhagic Disease-1 (RVHD-1)
  • Rabbit Viral Haemorrhagic Disease-2 (RVHD-2)
• Your rabbits’ first vaccinations should be around five weeks of age, after that they should have a booster injection every year.
• Our vets recommend vaccinating all pet rabbits, including house rabbits.

What vaccines do rabbits need and when?

Pet rabbits in the UK should be vaccinated against:

1. Myxomatosis
2. Rabbit Viral Haemorrhagic Disease-1 (RVHD-1)
3. Rabbit Viral Haemorrhagic Disease-2 (RVHD-2)

Your rabbits should have their first vaccine at around five weeks old, followed by a yearly booster to stay protected.

There are two vaccines now available in the UK: one that protects against all three diseases and another that protects against the new RVHD-2 strain detected in Europe. These vaccines should be given two weeks apart.

Should I vaccinate my house rabbits?

Yes, we recommend vaccinating both indoor and outdoor rabbits because Myxomatosis, RVHD-1, and RVHD-2 can all spread via insects (such as mosquitos and fleas), wild rabbits, and on surfaces such as clothes and shoes.

Side effects of rabbit vaccinations

As with any medication, vaccines can cause side effects. Fortunately, they are rare, usually very mild, and tend to resolve within 24-48 hours. Common vaccine side effects include lethargy (low energy), reduced appetite, and a small round swelling around the injection site. Call your vet for advice if you notice any side effects after a vaccination, especially if your rabbit stops eating.

How much is it to vaccinate a rabbit?

Vaccination costs vary from practice to practice – if you call your vet practice, they will be able to tell you how much they charge.

Published: March 2026